Endocrine Abstracts

Introduction: Women with breast cancer (BC) have an increased risk of developing thyroid cancer (TC), specifically papillary and follicular thyroid carcinomas at a median of 5 years. The aim of the present retrospective study is to describe the clinical characteristics of women who present this association.Results: A total of 260 patients with an authenticated TC who were the median age at diagnosis is 41 years old (36–65). All our patients live in ...

Introduction: Distant metastasis caused by thyroid carcinoma is common and usually found in lung or bone. Clinically detectebale, welldifferenciated metastatic thyroid carcinoma to the kidney is rare. Only 16 cases have been reported in the littérature. We describe a case of metastatic vesicular thyroid carcinoma to the bilateral kidneys in a 61 years women, with bone, pulmonary lever and lynph nodes metastasis.Case report: A 61 old women with a pas...

Introduction: The occurrence of a pregnancy in a woman with a corticotroph adenoma is rare, <25 observations have been reported.Maternal complications are especially hypertension (60–75%) gestational diabetes (25%) and preeclampsia in 10%.Fetal complications are spontaneous miscarriage, preterm birth and intrauterine growth retardation.Observation: We report a case of a 30 years old female followed f...

Introduction: Vandetanib is a multikinase inhibitor of the family of EGF receptor inhibitors whose main indication is medullary thyroid cancer at the locally advanced or metastatic stage. It is associated with cutaneous toxicity represented mainly by acneiform eruptions and hand-foot syndrome appearing a few weeks after the start of treatment. Folliculate is rare We report a rare case of late chronic folliculate of the lower limbs secondary to vandetanib.<p class="abstext"...

Introduction: Pregnancy is a test for the thyroid, which has many physiological adaptation mechanisms to increased hormonal needs and iodine depletion. These changes expose the pregnant woman to dysthyroidism not devoid of maternal and fetal consequences. The prevalence of clinical and subclinical thyroid insufficiency in pregnant women are 0.3 to 0.7% and 2.2 to 2.5%, respectively. The objective of this study is to evaluate the thyroid status in a population of diabetic pregn...

Introduction: Occult carcinoma of the thyroid is defined as a microcancer less than 1 cm in size, clinically undetectable. Discovered accidentally during routine radiological examination, cervical surgery of a benign thyroid tumor, varies from 0.01% to 35.6%. Mostly it is papillary type. Occult cancers revealed by bone metastasis have rarely been reported. We report two patient observations presenting bone localizations of occult thyroid carcinoma.Observ...

Introduction: Thymic neuroendocrine (NE) tumors associated with multiple endocrine neoplasia type 1 (MEN1) are rare, variably documented in 1–8% cases. They are malignant and aggressive tumors and form a major cause of mortality in MEN1.We report a case of thymic NE carcinoma developing rapidly after parathyroidectomy in a MEN1 patient.Case: A 45 years old man was allowed for headaches, the biology showed a hypercalcemia, a hy...

Introduction: Thyroid carcinoma accounts for 1% of all thyroid tumours. Bone metastasis occurs in 10 to 40%, with skullmetastasis accounting for 2.5 to 5.8% of bone metastases. The largest series of skull metastasis from thyroid carcinoma described a frequency of only 2.5% among 473 patients. The majority of skull metastasis from thyroid cancers is of the follicular subtype. She can occur at any age, the youngest patient was just 18 years old but most patients are between 60 a...

The commonest site of metastasis from papillary carcinoma is regional lymph nodes. Distant metastases are rare, most presenting synchronously. Brain metastases in papillary carcinoma are rare, reported with a frequency of 0.1–5% and cavernous sinus metastasis is extremely rare.Case report: A 62-year-old woman presented with a history of non-secretory pituitary macroadenoma present with symptoms of hypopituitarism. MRI of the brain revealed a 4.5&#21...

Introduction: Two patients admitted for evaluation of a hypercalcemia and hypothyroidism whose etiologic diagnosis showed itself unusual.Case no. 1: A 45 years old man allowed for disorders of consciousness, vomitings and headaches, biology showed a hypercalcemia, a hypophosphoraemia, hyperPTH. The imaging revealed parathyroidal adenoma with a compressive prolactinema. Pet Scan-FDG showed a metabolic activity of the thymic cavity with a necrotic aspect, ...